Potential Therapeutic Strategies and Substances for Facial Nerve Regeneration Based on Preclinical Studies
نویسندگان
چکیده
منابع مشابه
Nanotechnology for peripheral nerve regeneration
Peripheral nerve injuries (PNI) can lead to lifetime loss of function and disfigurement. Different methods such as conventional allograft procedures and using of biological tubes have problems for damaged peripheral nerves reconstruction. Designed scaffolds with natural and synthetic materials are now widely used in the reconstruction of damaged tissues. Utilization of absorbable and non-absorb...
متن کاملNanotechnology for peripheral nerve regeneration
Peripheral nerve injuries (PNI) can lead to lifetime loss of function and disfigurement. Different methods such as conventional allograft procedures and using of biological tubes have problems for damaged peripheral nerves reconstruction. Designed scaffolds with natural and synthetic materials are now widely used in the reconstruction of damaged tissues. Utilization of absorbable and non-absorb...
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It was traditionally thought that the central nerve system (CNS) defects the regenerated ability, following the injury. However, the peripheral nerve system (PNS) possesses an ability of regeneration after injury. Also it was found that the axon in CNS might extend into the graft, as soon as the peripheral nerve tissue was transplanted into the injured part of CNS. Therefore, it implied that th...
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UNLABELLED Posttraumatic facial paralysis is a frequent disease. This work studies posttraumatic regeneration of the facial nerve in rabbits. Functional and histological analysis compared injured and normal nerves on opposite sides. The left facial nerve trunk of twenty rabbits were subjected to compression lesion, and sacrificed after two (subgroup AL), four (BL) and six (CL) weeks. Comparison...
متن کاملMelatonin and its therapeutic actions on peripheral nerve regeneration.
Melatonin has many different roles in the human body, including its importance in circadian rhythms, sleep physiology, mental status, reproduction, tumour development, ageing, and many other physiologic processes. Although there are more than hundreds of studies on effects of melatonin in several tissues, its effects on peripheral nerve has been documented in a limited number of studies. This p...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2021
ISSN: 1422-0067
DOI: 10.3390/ijms22094926